Here are some PubMed stories I am interested in and have been following. Maybe you will be interested in some of the topics too:
Dietary Supplement Therapies for Inflammatory Bowel Disease: Crohn’s Disease and Ulcerative Colitis
Inflammatory bowel disease (IBD) including ulcerative colitis and Crohn’s disease are chronic relapsing and remitting chronic diseases for which there is no cure. The treatment of IBD frequently requires immunosuppressive and biologic therapies which carry an increased risk of infections and possible malignancy. There is a continued search for safer and more natural therapies in the treatment of IBD. This review aims to summarize the most current literature on the use of dietary supplements for the treatment of IBD. Specifically, the efficacy and adverse effects of vitamin D, fish oil, probiotics, prebiotics, curcumin, Boswellia serrata, aloe vera and cannabis sativa are reviewed.
All of the supplements listed in this survey have been talked about over the past 6 years on the iHaveUC site, and some of them in quite a bit of detail. There have been both positive and negative comments by the iHaveUC readers on nearly all of these supplements, so it will be interesting to see how Alyssa Parian (the study author) compiles the results, and how they look. I’ve sent her an email requesting a PDF of the study results and will update this posting if I receive them.
Impact of Surgery on Relationship Quality in Patients With Ulcerative Colitis and Their Partners.
Although social support is important for quality of life in patients undergoing surgery for ulcerative colitis, the impact of surgery on patient relationships is not known.
We examined relationship parameters in patients with ulcerative colitis and their partners before and 6 months after surgery.
Well come on, this is a pretty interesting study that I think most UC’ers are interested in learning about whether you have had surgery or not. Here is the link to the full abstract so you can read the study results and conclusion – Surgery and Relationship study results – click here.
The importance of vitamin D in the pathology of bone metabolism in inflammatory bowel diseases
Etiological factors of bone metabolism disorders in inflammatory bowel diseases have been the subject of interest of many researchers. One of the questions often raised is vitamin D deficiency. Calcitriol acts on cells, tissues and organs through a vitamin D receptor. The result of this action is the multi-directional effect of vitamin D. The reasons for vitamin D deficiency are: decreased exposure to sunlight, inadequate diet, inflammatory lesions of the intestinal mucosa and post-gastrointestinal resection states. This leads not only to osteomalacia but also to osteoporosis. Of significance may be the effect of vitamin D on the course of the disease itself, through modulation of the inflammatory mechanisms. It is also necessary to pay attention to the role of vitamin D in skeletal pathology in patients with inflammatory bowel diseases and thus take measures aimed at preventing and treating these disorders through the supplementation of vitamin D.
Some interesting reading indeed. This was a for sure eye opener when I got to this part of the study: “The incidence of low bone mineral density in patients with IBD is currently estimated at 31–59% . The pathogenesis of these disorders appears to be multifactorial, and vitamin D and calcium deficiencies, chronic inflammatory processes and the use of glucocorticoids have been mentioned as the main causes”
31-59%…holy crap right.
The link to the entire study is here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624748/
That’s all for now.
If you are interested in reading more PubMed Stories (this is the super massive database of clinical and scientific studies), I would highly encourage you to read my post titled: How to Use PubMed – It’s Super Easy.
For those who have been following the site for 6 six years, my apologies for beating home this idea on getting off your bass and getting on pubmed to educate yourself…sorry, but probably not my last time touting pubmed…its friggin incredible indeed.
One more mention is that you have not watched the video interview I shot recently with the Aaron (the colitis triathlete superstar…father of a few…and doctor… here is the link to Aaron’s Video Interview – click here)
Enjoy your week and weekend,
I started site and the eNewsletter(you can join that below) shortly after being diagnosed with ulcerative colitis in October of 2008 with severe pancolitis (when my whole colon was inflamed).
For me, it was a very rough start with severe symptoms. Getting bounced from medication to medication was not easy or too helpful. But, I did meet another UC’er, changes several parts of my diet, and of course the rest is history.
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