Recent Ulcerative Colitis Research Studies

Today, I did a bit of a look through PubMed (the online database of literally millions of studies and research articles available to anyone), and there were a few interesting full text articles that popped out which I think might be of interest to you.

Here is the list of studies and the links to the full text articles should you wish to check them out:

• COVID-19 Vaccine Booster Dose Willingness among Patients with Inflammatory Bowel Disease on Infliximab and Vedolizumab: A Cross-Sectional Study.
  • Full Study Text to read with related graphs and images – CLICK HERE
  • Something I found interesting from the “conclusion” section: “Patients treated with infliximab were more likely to be willing to receive a third (booster) dose of COVID-19 vaccine.”
• Ulva pertusa, a Marine Green Alga, Attenuates DNBS-Induced Colitis Damage via NF-κB/Nrf2/SIRT1 Signaling Pathways
  • Full Study Text is here: Marine Green Alga and UC Study
  • This is a very scientific (not the easiest simple language to read study), but the ideas behind is very progressive with other current studies involving the pathways that lead to IBD symptoms. Let me know if you like this type of study, as there are many more to review
  • Also of note, this study was based in Messina, Italy, and if you are interested in more details, I’m sure you can email Alessio Ardizzone who is listed as the lead for this research, and you should get a response
• The Effects of Fatty Acids on Inflammatory Bowel Disease: A Two-Sample Mendelian Randomization Study
  • Full link to read this located here
  • The Fatty Acids relation (or not) to IBD is very controversial, as they state within this particular study, as is the case with many topics for our disease unfortunately
  • Interesting and potentially beneficial part of the conclusion of this study: “Omega-3 FA was observed to have a protective effect against UC, providing a new perspective on the investigation of the associations between FAs and IBD.”
• Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer
  • This was my personal favorite study of the day, lots of topics covered. Below is the brief Abstract of this study, if this seems interesting to you the full study should be as well:
    • “The gut microbiome has increasingly been recognized as a critical and central factor in inflammatory bowel disease (IBD). Here, we review specific microorganisms that have been suggested to play a role in the pathogenesis of IBD and the current state of fecal microbial transplants as a therapeutic strategy in IBD. We discuss specific nutritional and dietary interventions in IBD and their effects on gut microbiota composition. Finally, we examine the role and mechanisms of the gut microbiome in mediating colitis-associated colon cancer.”
  • Full study can be enjoyed here: Full study details
  • Below is an image that might get you interested in this particular IBD study. Also, most of the participants from the “scientist” angle are based out of Stanford Hospital, in California.

So there you go, a few studies to look through. And again, if you have any interest in doing more research, or if you want to follow up directly with the scientists who conducted the different studies listed, I would highly encourage you to do so. They almost always list their email addresses on the study details (that is the case for all the studies listed in this post), and more often then not they are happy to respond to questions that you may have.

Thank you again for being a part of the website,

Adam

Adam

I started site  shortly after being diagnosed in October of 2008 with severe pancolitis (when my whole colon was inflamed).

For me, it was a very rough start with severe symptoms.  Getting bounced from medication to medication was not easy or too helpful.  But, I did meet another UC’er, changes several parts of my diet, and of course the rest is history.

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