Wrote once before about my son who has severe UC. It had been 1 1/2 years since on set of UC. He has been on Apriso, Imuran, suppositories, prednisone for almost this entire time, each time working his way down on predinose, getting below 15 and UC getting worse each try. Starting back on 40 again. Now they have put him on Humira, 40 mg injector pens. Did the initial starter pack then every other week. Started to feel better, then UC started getting worse again. Now he is on shots weekly,plus Apriso and Imuran. Has started feeling better the last week. He also went to the Mayo Clinic in Minnesota. Nothing different other than keep taking the medicine.