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Asacol / Delzicol Reviews

Asacol Mesalazine

***UPDATE, Asacol has largely been discontinued/rebranded and replaced with “Delzicol”

Asacol / Asacol HD (also know as Masalazine or Mesalamine) is a relatively common medications that is prescribed for ulcerative colitis patients.  Asacol is within the family of 5-aminosalicylic acid (5-ASA) drugs, and it is used as an anti-inflammatory medication which is targeted specifically for people with inflammatory bowel disease.

Manufacturer: Allergan

There is tons of information available online with regards to published studies on medications in the 5-ASA family.
Some recent studies:

If you have taken Asacol and would like to submit your own review of your experience with the medication, please feel free

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Average rating:  
 74 reviews
 by Marsha Crippen
Asacol vs. Delzicol, scared

I have had UC since 2000. I have mostly been on Asacol since the beginning with a few attempts at others. Delzicol was one of them. It did not hold off the flares like Asacol. I am currently on Asacol HD 800 6 pills / day. I have just heard Asacol is going or has been discontinued. I'm so very scared. Delzicol did not hot off the flares. Asacol has kept me in remission with maybe only 1 / 2 flares per year.

 by Shana

Asacol (then Delzicol after it rebranded) kept me in remission for 8 years! The first week of being on it was rough (symptoms were a bit worse, felt so bad I couldn't leave the house, but it was worth it. I was about a 10-12 month struggle to get fully into remission with multiple changes between Lialda, Prednisone, Delzicol, elimination diets to find trigger foods etc. But once my symptoms were under control I had a normal life. I traveled, ate street food, and even got food poisoning without my UC giving me any trouble. I only ended up back in a flare because 8 years of peace and some self-destructive tendencies brought about by depression convinced me to try going without my meds. I highly recommend Delzicol and I hope it works for me again in the future!

 by David

I was diagnosed in 2004. I have always had a mild case, with a few minor flares per year. I might go a year or more without a flare. I have been on asacol/delzicol since diagnosis. It seems to keep me mostly in remission. I went without taking them for 6 months once and eventually got a flare after about 6 months. No side effects that I can tell.

 by Heather

I was newly diagnosed and was not having symptoms after using hydrocortisone enemas. I was prescribed Asacol for maintenance. I was told to take more as time went on. Once I started it my symptoms returned. The more I took the worse they were. If I stopped taking it the symptoms would subside. Needless to say I don’t take it anymore and use cortisone for flares.

 by Rod
Worked for awhile

Mesalamine worked for 4 or 5 months, then pfffft. Then It didn't.

 by MStar

I was 55 when I started with UC. It was sort of low level IBS kind of issues, then low speed ulcers and ASACOL (400/3x/day) helped. But over time, when I did start having periods of active UC and needed something stronger (6MP 50mgs/day) asacol couldn't handle the UC as it got worse. I also used Prednisone (starting at 20-30 mgs/da) when I had a flare, for a couple weeks at least. Then back to sustainment with asacol, 6MP... But the Dr did increase the asacol to 1600mgs/3x/day to see if that might be a solution. Well.... long story short I switched GI Drs after two years. We can talk about that offline if you like My new GI Dr has taken me off asacol altogether, that was 3 months ago, and I'm doing fine without it... but I did start taking Remicade 6 months ago and its beginning to really take effect with my UC problem pretty much quiet right now.

 by Alisa
Only worked temporarily

I took Asacol for many years off and on at 3 pills, 3 times a day. Even when I was very disciplined with it (and I wasn't always disciplined with it in my 20s), it only worked well for about 3-4 weeks and then symptoms would return. I didn't see lasting change until I changed my lifestyle, stress patterns and diet.

 by Sam

I always felt this drug had no impact for me as it never got me into remission and I flared whilst taking it as a 'maintenance' drug. I always had a sore throat whilst taking it and felt terrible. I decided to stop taking it during the last flare up as an experiment and within a week my symptoms had completely gone! I hadn't felt better in years! I haven't taken it since. I've had a few minor flares since then but never had the terrible bleeding I suffered whilst on Asacol.

 by Connie Eicher
Mesalamine maintains at about 60%.

Mesalamine pills help 65% with no side effects. The mesalamibe enemas and suppositories worked well after 2 months.

 by Afshan

I was given Asacol when I was diagnosed with Colitis. I took 6 pills per day. It worked Partly for few months. I was on it for few years but I got many flare ups. I did not have any side effects.
I changed my doctor since he was ignoring my symptoms. My new doctor changed it to Imuran.

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2 thoughts on “Asacol / Delzicol Reviews”

  1. Wendy

    I have taken Asacol and the only thing it did for me was give me severe joint aches to where it hurt to move in the morning. I did not get better on it nor did it make me stay in remission.

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