***UPDATE, Asacol has largely been discontinued/rebranded and replaced with “Delzicol”
Asacol / Asacol HD (also know as Masalazine or Mesalamine) is a relatively common medications that is prescribed for ulcerative colitis patients. Asacol is within the family of 5-aminosalicylic acid (5-ASA) drugs, and it is used as an anti-inflammatory medication which is targeted specifically for people with inflammatory bowel disease.
There is tons of information available online with regards to published studies on medications in the 5-ASA family.
Some recent studies:
- Long-Term Mesalamine Maintenance in Ulcerative Colitis: Which is More Important? Adherence or Daily Dose.
- Medication use patterns and predictors of nonpersistence and nonadherence with oral 5-aminosalicylic acid therapy in patients with ulcerative colitis.
- Mesalamine in the treatment and maintenance of remission of ulcerative colitis.
- Exacerbation of bloody diarrhea as a side effect of mesalamine treatment of active ulcerative colitis.
If you have taken Asacol and would like to submit your own review of your experience with the medication, please feel free
Submit your review
I have had UC since 2000. I have mostly been on Asacol since the beginning with a few attempts at others. Delzicol was one of them. It did not hold off the flares like Asacol. I am currently on Asacol HD 800 6 pills / day. I have just heard Asacol is going or has been discontinued. I'm so very scared. Delzicol did not hot off the flares. Asacol has kept me in remission with maybe only 1 / 2 flares per year.
Asacol (then Delzicol after it rebranded) kept me in remission for 8 years! The first week of being on it was rough (symptoms were a bit worse, felt so bad I couldn't leave the house, but it was worth it. I was about a 10-12 month struggle to get fully into remission with multiple changes between Lialda, Prednisone, Delzicol, elimination diets to find trigger foods etc. But once my symptoms were under control I had a normal life. I traveled, ate street food, and even got food poisoning without my UC giving me any trouble. I only ended up back in a flare because 8 years of peace and some self-destructive tendencies brought about by depression convinced me to try going without my meds. I highly recommend Delzicol and I hope it works for me again in the future!
I was diagnosed in 2004. I have always had a mild case, with a few minor flares per year. I might go a year or more without a flare. I have been on asacol/delzicol since diagnosis. It seems to keep me mostly in remission. I went without taking them for 6 months once and eventually got a flare after about 6 months. No side effects that I can tell.
I was newly diagnosed and was not having symptoms after using hydrocortisone enemas. I was prescribed Asacol for maintenance. I was told to take more as time went on. Once I started it my symptoms returned. The more I took the worse they were. If I stopped taking it the symptoms would subside. Needless to say I don’t take it anymore and use cortisone for flares.
Mesalamine worked for 4 or 5 months, then pfffft. Then It didn't.
I was 55 when I started with UC. It was sort of low level IBS kind of issues, then low speed ulcers and ASACOL (400/3x/day) helped. But over time, when I did start having periods of active UC and needed something stronger (6MP 50mgs/day) asacol couldn't handle the UC as it got worse. I also used Prednisone (starting at 20-30 mgs/da) when I had a flare, for a couple weeks at least. Then back to sustainment with asacol, 6MP... But the Dr did increase the asacol to 1600mgs/3x/day to see if that might be a solution. Well.... long story short I switched GI Drs after two years. We can talk about that offline if you like My new GI Dr has taken me off asacol altogether, that was 3 months ago, and I'm doing fine without it... but I did start taking Remicade 6 months ago and its beginning to really take effect with my UC problem pretty much quiet right now.
I took Asacol for many years off and on at 3 pills, 3 times a day. Even when I was very disciplined with it (and I wasn't always disciplined with it in my 20s), it only worked well for about 3-4 weeks and then symptoms would return. I didn't see lasting change until I changed my lifestyle, stress patterns and diet.
I always felt this drug had no impact for me as it never got me into remission and I flared whilst taking it as a 'maintenance' drug. I always had a sore throat whilst taking it and felt terrible. I decided to stop taking it during the last flare up as an experiment and within a week my symptoms had completely gone! I hadn't felt better in years! I haven't taken it since. I've had a few minor flares since then but never had the terrible bleeding I suffered whilst on Asacol.
Mesalamine pills help 65% with no side effects. The mesalamibe enemas and suppositories worked well after 2 months.
I was given Asacol when I was diagnosed with Colitis. I took 6 pills per day. It worked Partly for few months. I was on it for few years but I got many flare ups. I did not have any side effects.
I changed my doctor since he was ignoring my symptoms. My new doctor changed it to Imuran.
So I like UC’ers. That’s been going on since 2009 I’d say.
I started site and the eNewsletter(you can join that below) shortly after being diagnosed with ulcerative colitis in October of 2008 with severe pancolitis (when my whole colon was inflamed).
For me, it was a very rough start with severe symptoms. Getting bounced from medication to medication was not easy or too helpful. But, I did meet another UC’er, changes several parts of my diet, and of course the rest is history.
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