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The Latest UC Research

Here are some PubMed stories I am interested in and have been following.  Maybe you will be interested in some of the topics too:

Dietary Supplement Therapies for Inflammatory Bowel Disease: Crohn’s Disease and Ulcerative Colitis

Abstract:

Inflammatory bowel disease (IBD) including ulcerative colitis and Crohn’s disease are chronic relapsing and remitting chronic diseases for which there is no cure. The treatment of IBD frequently requires immunosuppressive and biologic therapies which carry an increased risk of infections and possible malignancy. There is a continued search for safer and more natural therapies in the treatment of IBD. This review aims to summarize the most current literature on the use of dietary supplements for the treatment of IBD. Specifically, the efficacy and adverse effects of vitamin D, fish oil, probiotics, prebiotics, curcumin, Boswellia serrata, aloe vera and cannabis sativa are reviewed.

My thoughts:

All of the supplements listed in this survey have been talked about over the past 6 years on the iHaveUC site, and some of them in quite a bit of detail.  There have been both positive and negative comments by the iHaveUC readers on nearly all of these supplements, so it will be interesting to see how Alyssa Parian (the study author) compiles the results, and how they look.  I’ve sent her an email requesting a PDF of the study results and will update this posting if I receive them.

Impact of Surgery on Relationship Quality in Patients With Ulcerative Colitis and Their Partners.

Abstract:

BACKGROUND:

Although social support is important for quality of life in patients undergoing surgery for ulcerative colitis, the impact of surgery on patient relationships is not known.

OBJECTIVE:

We examined relationship parameters in patients with ulcerative colitis and their partners before and 6 months after surgery.

My thoughts:

Well come on, this is a pretty interesting study that I think most UC’ers are interested in learning about whether you have had surgery or not.  Here is the link to the full abstract so you can read the study results and conclusion – Surgery and Relationship study results – click here.

The importance of vitamin D in the pathology of bone metabolism in inflammatory bowel diseases

Abstract:

Etiological factors of bone metabolism disorders in inflammatory bowel diseases have been the subject of interest of many researchers. One of the questions often raised is vitamin D deficiency. Calcitriol acts on cells, tissues and organs through a vitamin D receptor. The result of this action is the multi-directional effect of vitamin D. The reasons for vitamin D deficiency are: decreased exposure to sunlight, inadequate diet, inflammatory lesions of the intestinal mucosa and post-gastrointestinal resection states. This leads not only to osteomalacia but also to osteoporosis. Of significance may be the effect of vitamin D on the course of the disease itself, through modulation of the inflammatory mechanisms. It is also necessary to pay attention to the role of vitamin D in skeletal pathology in patients with inflammatory bowel diseases and thus take measures aimed at preventing and treating these disorders through the supplementation of vitamin D.

My thoughts:

Some interesting reading indeed.  This was a for sure eye opener when I got to this part of the study:  “The incidence of low bone mineral density in patients with IBD is currently estimated at 31–59% [1]. The pathogenesis of these disorders appears to be multifactorial, and vitamin D and calcium deficiencies, chronic inflammatory processes and the use of glucocorticoids have been mentioned as the main causes”

31-59%…holy crap right.

The link to the entire study is here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624748/

 

adamThat’s all for now.

If you are interested in reading more PubMed Stories (this is the super massive database of clinical and scientific studies), I would highly encourage you to read my post titled: How to Use PubMed – It’s Super Easy.

For those who have been following the site for 6 six years, my apologies for beating home this idea on getting off your bass and getting on pubmed to educate yourself…sorry, but probably not my last time touting pubmed…its friggin incredible indeed.

One more mention is that you have not watched the video interview I shot recently with the Aaron (the colitis triathlete superstar…father of a few…and doctor… here is the link to Aaron’s Video Interview – click here)

Enjoy your week and weekend,

Adam Scheuer

 




pubmed, vitamin d

6 Responses to The Latest UC Research

  1. noelgallagirl November 17, 2015 at 12:20 pm #

    As ALWAYS…thank you Adam!

    Of course there needs to be better therapies for treating UC.

    The meds are complete overkill and potentially more harmful than the UC itself.

    I keep crossing my fingers for a natural treatment that will work for EVERYONE.

    :)

    • UC Family Boy
      Uc family boy November 25, 2015 at 12:28 pm #

      Well said!

      I’m glad current research, patient participation has helped lead us towards learning that individual treatment isn’t far away.

      Targeting these pathways (that causes uc) alongside addressing the microbiota could be the future.

      May also explain why what works for some might not for others….

  2. Heidi November 17, 2015 at 2:01 pm #

    Thank you so much for bringing attention to this, Adam. I personally have difficulty maintaining adequate vitamin D levels and it’s probably no coincidence that my vit D level was way low when my UC showed up. I also developed osteoporosis after my diagnosis and about an 8 month stint on prednisone. I haven’t taken the medication my Dr prescribed (Risendorate) out of fear of the side effects. I’d be curious to know how others have dealt with low vitamin D and osteoporosis

    I have also read somewhere that chubby folks have vitamin D dysregulation. (I’m one of those too:-/).

    I’m taking 8-10 000 units of vitamin D a day, about 500 mg of calcium in supplement form plus I eat cheese , drink mineral water and bone broth daily, and a big dose of vit K2 (to hopefully make sure the calcium goes where it belongs). I’d appreciate input if anyone has advice.

  3. Larry November 17, 2015 at 7:44 pm #

    Adam thanks so much for this information on vitamin D, in the last year my vitamin D level has fallen about 3 to 4 points, in addition I go to the VA hospital so I get very little help from the doctors. Keep up the good work and send anything else that will help us. THANKS AGAIN.

    Larry

  4. Chandan November 17, 2015 at 10:06 pm #

    Hi Adam,
    Thanks for coming up with the latest developments related to Ulcerative colitis. What i have to say is, after i took pure cabbage juice for around 14 days, i am way better than i was before. Medication didn’t help me much to be honest.

  5. Richard Brownson November 18, 2015 at 8:35 am #

    Hi Adam, in the last 6 months of been getting itchy dry skin spots. Do you think this could be related to low Vitamin D levels and could taking Vitamin D supplements help with it?

    Thanks

    Rich

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