Unlike biologics, which target extracellular molecules such as pro-inflammatory cytokines, tofacitinib targets the intracellular signaling pathways that operate as hubs in the inflammatory cytokine network. It’s goal is to reduce the inflammatory response much like several other medications that are currently FDA approved.
Intro: I was diagnosed with UC, January 13, 2015 immediately after my colonoscopy. My symptoms started to appear the previous year, first in July – blood was present in my stool for one week, and then it went away. My second flare-up happened in October and it lasted for 3 weeks. Still I ignored it, […]
Lane talks about his battle with ulcerative colitis and how he has moved from Humira which caused skin reactions to Azathiprine and Simponi.
Meet Hanneke. She talks about her 11 years in remission. Hanneke actually wrote: “That’s what my doctor calls it. I do have very minor flare ups and since I have this for so long I feel exactly when it’s coming up. I manage it myself with my meds. I never really go into a full […]
Hi, My name is Timo, I’m 65 retired computer and electronics engineer and author. My motive is to share my positive experiences how I’ve managed to improve the quality of my life with Ulcerative Colitis. The daily need to go to toilet is one or two times. Below I’ll tell you what I did.
I was first diagnoses with Ulcerative Colitis in 2009 and eventually had to have the total colectomy and ileoanal pouch surgery. The final surgery was completed in February 2014 and all was well until recently. I saw my GI this afternoon and am scheduled for a colonoscopy in 2 weeks time.
I am a scholarship track and field athlete at the University of California, Berkeley. I am originally from San Diego, and I really enjoy surfing, rock climbing, and anything that is active and engaging!
Video where Stephanie explains and answers questions of how Remicade has turned into a major success story for her and her ulcerative colitis. She has many days where she forgets she even has anything wrong, learn all the details in her interview available to view right now.
Joyce’s Ulcerative Colitis seems to be in complete remission but she still experiences the chronic rectal pain. A heating pad relieves it somewhat. Sitting and standing for a period of time makes it worse. Lying down at bedtime, her pain gradually subsides, and she doesn’t have problems sleeping through the night.
Meet Jay: Diagnosed 2009, via colonoscopy, really scary time thought I had cancer. Symptoms started with thousands of tiny sores on insides of my hands and fingers, found out these were ulcers. My mouth was full of ulcers and I couldn’t stop going to the toilet, not the best when your a swim teacher in […]