With so many different supplements available to the hundreds of thousands of UC’ers around the world, it can be very hard if not impossible at times to decide upon what might help you out or not.
So, once again, if you have any experience yourself with L-Glutamine (or just plain “glutamine” as some people do call it by a different name even though there’s no difference), definitely let the rest of the UC’ers of the site know your thoughts.
From wikipedia’s page:
Here are some scienctific studies with regards to Glutamine and Colitis:
- Glutamine supplementation attenuates expressions of adhesion molecules and chemokine receptors on T cells in a murine model of acute colitis.
- Effects of dietary glutamine on the homeostasis of CD4+ T cells in mice with dextran sulfate sodium-induced acute colitis.
- Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis.
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Saved me from Steroids
Have had UC since I was 22 and am now 39. Hospitalized 3 times after having severe reactions to prescribed UC meds. Only thing that would put me in remissions was long bouts of high amounts of steroids which tore my body down. Started doing my own research and read about L-Glutemine. Every time I start seeing symptoms or get upset stomach I take it in the morning and in the evening before food. It has literally changed my life. Stops cramping, bleeding and after a couple week any other signs of UC flare up! My heart goes out to anyone suffering with this ugly disease. Be blessed!
Total remission for 3 years
Some background about my UC before I talk about my experience with L-glutamine- I've been diagnosed for over 10 years. Sometimes symptoms were that bad and I was losing so much blood that I've had to be admitted to hospital. I used to take mesalamine both orally and rectally for treatment but didn't like what I'd read about steroidal treatments so avoided those. I tended to have 2-3 flare ups a year each lasting around 2 months and I wasn't sure the meds were being effective. I read a lot of medical studies, as I'm sure many of you have, and I decided whilst in the middle of a bad flare to experiment with L-glutamine, Aloe vera and probiotic capsules. My symptoms cleared up in a week and I've never had a severe flare 3 years later. I don't take any of these things regularly (perhaps I should!) but if I start to feel any warning signs I make sure I start taking them again. At first I wasn't sure which component was having the most effect but I have since just used L-glutamine on its own and any pre-symptoms of a flare have subsided quickly. I do believe however the aloe vera and pro-biotics helped in the middle of a flare the alleviate the discomfort. I no longer take any medication and am free to eat (and drink) whatever I like - this includes things I would have avoided in the past: coffee, straight spirits, heavily spiced food. I realise these things some to behave very differently in different people but I'm convinced that the L-glutamine has had an impact in my life. In terms of dosage I never went crazy. Just took 1-2 500mg capsules before breakfast everyday and as I said when I have no symptoms for a while I don't bother.
19 years of diagnosed UC. I had just finished a 6 week course of prednisone to deal with a bad flare up and my wife read a study about L-Glutamine. I started with 1500mg per day and have been totally symptom free for 3 months including 1 month with no other drugs for the first time in 19 years. It really worked for me
L-Glutamine hasn't worked
At the suggestion of my (awesome!) nutritionist, I tried L-Glutamine in both capsule and powder form. Both worsened my UC symptoms - Made the stool mucusy and watery and urgent and frequent, which was not fun. I've never tried it for more than two or three days at a time.
L-glutamine for treatment of UC
I have been using l-glutatime for treatment of my ulcerative colitis for a couple of month. Problem is I am not always consistent with taking it. I must say that the times I have used it, I did notice a difference and and things seem to get better. I'm not real clear on what dosages I should be taking either. I need more instruction and information. I've read so may different articles about this amino acid being able to help with UC that I do believe it helps, you just have to be consistent. I still take my conventional medications and I use probiotics as well. I am so tired of taking so much medication, even taking the l-glutamine gets old. I have seen a positive effect when I take it. The max dosage I tried was one heap teaspoon per day.
Mild Lt side UC dx in 2010, responded to Llialda with a few flares afterwards but never was able to get rid of the urgency or loose stools. After reading reviews of L glutamine on this site I decided to give it a try along with a strong probiotic. Within 2 days my stools were firm and formed and I had no urgency whatsoever. Its only been 3 weeks but i have reduced my Llialda intake dramatically and feel great. This is a game changer for me since I avoided going out if a bathroom was not readily available. TY Adam for this informative website which allows people with the disease to disseminate information that may not be available from our clinical providers.
After reading about supplelemts to help my UC, Lglutemine was one of the first I bought as well as Bromeline. Both oF them together with food every morning was a great help in keeping my flairs at bay. Definitely recommend L Glutemine. Oh and also ALoe Vera juice !!
I tried Glutamine a couple of times and it gives me a major headache with no noticable effect.
What really made a difference for me has been heavy doses of Vitamin D & K, plus extra magnesium, calcium and boron. People with UC have an imbalance with their intestinal flora., which is linked to K2 deficiency. K2 is linked to calcium and D absorption as well and they all work together to regulate the immune system. Once I began increasing those vitamins and minerals, my symptoms have decreased. I also take colloidal minerals with enzymes to assist with digesting grains and dairy. Pro-biotics keep my flora going strong as well.
I bout it when i followed jini patels protocol. It made zero difference with my diarrhea. I also took it during other flares but was still hospitalized and on prednisone during these times. The max dose i tried was 15 grams per day.
I've been using L-Glutamine for a year and a half and it has stopped the blood! After being hospitalized in Feb 2013, I started taking L-Glut after tapering out of a 6 week Prednisone treatment. (this is when I joined this community!) I have been symptom free since April 2013 by taking L-Glut, vitamin D, VSL, Apple Cidar Vinegar in AM and Afternoon, Multivitamin, Fish oil, Aloe Juice, Tumeric, and slippery elm (late afternoon and evenings). This combo has saved me from a flare!
I also attend accupunture 2-3 times a month when I'm feeling bloated (usually in conjunction with PMS) Community accupuncture clinic donation based fee (very affordable). Vinyasa Yoga and Walking 2-3 days a week. To the person who is concerned about cost, I've found very affordable websites such as Sundrops.com and my local health/food market/collective to buy supplements. I spend about $80 to $200 every 3 months or so; but I think this is worth investing in my health and not being on prescriptions. :)
Ever since I read about L-Glutamine on this website I ordered it immediately. I started taking one pill every day. That was about 2 months ago. Immediately I saw results in a healthier bowel movement (more firm). I am not sure what else it is doing, but I will definitely continue using it.
One bullet in my arsenal...
I first started taking powdered L-Glutamine during my first flare - I did not notice much of a difference at that time, but nothing except for 2 months of prednisone was able to get my healing to start. I have found that when I start to feel symptoms creeping up it seems to help - as long as they aren't too out of control. This summer I have been making a frozen banana treat in the vitamix almost every day (better than ice cream and easier on my tummy!) - I always add 1-2 big tablespoons of L-Glutamine and am doing well. I'm a fan.
I started supplementing with L-Glutamine last year while beeing in a severe flare that landed me in the hospital.I took it for about2 months.It did neither help nor hurt me.Maybe my muscle soreness got better but I'm not sure that came from this supplement. I also stsrted taking Magnesium so maybe that helped with muscle soreness.
Glutamine helps stop the bleeding!!!
Yes, there are SO many supplements out there! We would all be broke if we took everything that we wanted to take... I had a HORRIBLE flare up for months in 2012... I finally got it semi-under control (where I could leave the house, but was still feeling pretty crappy) but I was still bleeding all the time and a holistic nurse recommended that I add Glutamine to the other bazillion supplements that I take... so I tried it... and 3 days later, the bleeding stopped! I took Glutamine every day for at least a year after that. I stopped taking Glutamine simply because now I have other issues that I am dealing with and I am spending my money on other supplements. I highly recommend the Glutamine, especially if you have bleeding issues. I used a small wire whisk and mixed mine with coconut water and chugged it down. -- All the best to all of you